Vitamin B12 Deficiency Guide

Vitamin B12 Deficiency Guide

 What is Vitamin B12 and what does it do?

Vitamin B12 helps to keep the body’s nerve and blood cells healthy. Vitamin B12 is a water-soluble vitamin which is important for the human body to make red blood cells, nerves, DNA and other functions. It is not synthesised by the body and thus Vitamin B12 rich foods should be included in the diet.

What causes Vitamin B12 Deficiency?

Vitamin B12 Deficiency can begin in cases if vitamin B12 is not occupy from the food properly, pernicious anemia, improper absorption due to post surgical treatment and insufficient intake of Vitamin B12 in the diet.

The abnormal or poor absorption of Vitamin B12 can be seen in conditions like pernicious anemia (decrease in red blood cells due to deficiency of Vitamin B12), celiac disease (immune reaction to gluten), inflammatory bowel diseases (inflammation of digestive tract), overgrowth of bacteria or presence of parasites such as tapeworms in the intestines, reduction in stomach acid production (due to long term use of antacids), gastric bypass (surgery that removes part of the stomach), insufficiency of pancreas (inability to digest food properly).

Factors such as smoking, drinking heavy alcohol or chronic (from a long time) alcoholism, pregnancy can cause a deficiency of Vitamin B12.

What are the symptoms of Vitamin B12 Deficiency?

Following are the signs and symptoms which could be seen in person with Vitamin B12 Deficiency:

  • Pale skin
  • Weakness
  • Tiredness
  • Feeling of pins and needles
  • Change in walking pattern
  • Ulcers in mouth
  • Redness of tongue
  • Shortness of breath
  • Blurring of vision
  • Mood swings

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The deficiency of Vitamin B12 results in macrocytic anemia (size of red blood cells larger than normal).

Megaloblastic anemia is a type of macrocytic anemia, in which large size red blood cells called as macrocytes are produced. These red blood cells are fewer in number. There is a decrease in white blood cell count and platelet count. Megaloblastic anemia occurs due to acquired deficiency of Vitamin B12. The reason can be an inadequate dietary intake of Vitamin B12 or any problem in the absorption of Vitamin B12 from the intestines.

How to detect Vitamin B12 Deficiency?

You can get your Vitamin B12 levels checked by a simple blood test. The normal range of Vitamin B12 is 211 – 911 pg/mL irrespective of sex and age.

Increased levels of Vitamin B12 may be seen in kidney failure, diabetes, liver disease etc.

Decreased levels of Vitamin B12 may be seen in anemia, hyperthyroidism (high levels of thyroid), worm infection etc.

How to treat Vitamin B12 Deficiency?

Vitamin B12 rich foods can be included in the diet such as fish, red meat, eggs, milk and milk products, legumes, nuts, seeds and soy products to treat the deficiency. Vitamin B12 deficiency is common in vegetarians as plant foods don’t have Vitamin B12. Oral supplements of Vitamin B12 are recommended for treatment. Vitamin B12 injections are also available in the form of cyanocobalamin.

In case, Vitamin B12 Deficiency is due to pernicious anemia, parenteral administration of Vitamin B12 is preferred. Vitamin B12 supplements are also available in the form of a gel that can be applied intranasally as an alternative to Vitamin B12 injections.

Severe deficiency of Vitamin B12 can lead to blood diseases and neurologic problems. Therefore, it should not be ignored.

13 Diseases: Vitamin D Deficiency

13 Diseases: Vitamin D Deficiency

13 Common Diseases Caused by Vitamin D Deficiency

Vitamin D deficiency is more common than you might think. Actually, it’s so common the American Journal of Clinical NutritionIt called it a worldwide issue that is recognized as a pandemic. Know Supplements is explaining here about 13 Common Diseases Caused by Vitamin D Deficiency. Additionally, a poll in the UK revealed that more than half of adults in the UK didn’t have sufficient vitamin D, also at the spring and winter roughly 1 in 6 individuals have a serious lack.

What’s vitamin D?

Vitamin D is essential to get fantastic general health and plays an essential part in ensuring our muscles, lungs, heart and brain function nicely. Our body can make its own vitamin D from the sun. You can also get vitamin D from supplements, and a tiny amount comes out of a couple of foods that you consume, such as a few fish, fish liver oils, egg yolk and also in fortified dairy, cereals and grain products.

Why is vitamin D exceptional in comparison to other vitamins is your body can make its own vitamin D when you expose your skin to the sun, whereas you want to acquire different vitamins in the foods that you consume.

How long should you invest in the sun to get sufficient vitamin D?

Learning how long to keep in sunlight to be able to create enough quantities of vitamin D can be extremely catchy and can be different for each and every individual, hence there is not 1 recommendation for everybody. The cause of that is the period of time you want to spend in sunlight for the skin to create enough vitamin D is dependent upon a range of aspects, like how dark your skin is how readily you get sunburnt, the depth of the ozone layer, the period of this year and what time of day it is.

It’s thought that brief daily period of sunlight without sunscreen (approximately 10-15 minutes to get lighter-skinned individuals ) through the summer months is sufficient for most people to produce enough vitamin D. Evidence indicates that the best time daily for vitamin D production is between 11 am and 3 pm. The bigger the area of the skin that’s exposed to the sun, the more chance there is of creating enough vitamin D until you begin to burn.


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Common causes for Deficiency of vitamin D

  • Restricted exposure to the sun — Many people live in northern latitudes, wear long clothing, or are employed that’s taken place mostly inside. Additionally, pigment inhibits vitamin D generation.
  • Dark epidermis — Individuals with dark skin have high levels of saliva, also this pigment reduces the skin’s capacity to generate vitamin D when exposed to the sun.
  • Kidney and liver function — These organs play a significant role in converting vitamin D into its active form, therefore liver or kidney diseases can lower the ability of the organs to produce the biologically active form of vitamin D within the body.
  • Spicy vegetarian diet — Food sources which include vitamin D are for the most part animal-based, including fish and fish oils, egg yolk, cheese, fortified milk, and beef liver.
  • Digestive problems — Specific medical conditions, such as Crohn’s disease, cystic fibrosis, and celiac disease can lower the ability of the intestines to absorb vitamin D from food.
  • Fatness — Fatness can cause low vitamin D levels. Research indicates that vitamin D can become’trapped’ within fat tissue less of it’s offered in our blood flow.

Vitamin D Deficiency Associated Diseases & Conditions

Maintaining suitable vitamin D levels is among those 70 habits featured within my e-book 70 Powerful Habits To Get A Great Health that will lead you the way you can take positive actions to increase your wellbeing and general wellbeing. Researchers are still working to fully understand how vitamin D functions inside our own body and how it influences our General Health, but it’s Thought to Be a connection between vitamin D deficiency to a significant number of disorders:

1. Osteoporosis — A decent amounts of calcium and vitamin D are essential for maintaining bone strength and density. Too little vitamin D induces calcium-depleted bone, which weakens the bones and increases the risk of fractures. It is also possible to read my post about the 4 measures to avoid osteoporosis.

2. Infection — Vitamin D deficiency is closely connected to reduced lung acts and much worse asthma management, particularly in kids. Vitamin D can improve asthma management by blocking inflammation-causing proteins in the gut, in addition to increasing production of another protein that has anti-inflammatory consequences. Read this post about natural remedies for asthma, which vitamin D is among these.

3. Heart health — Vitamin D deficiency can be connected to a greater chance of elevated blood pressure (hypertension) and elevated risk of death from cardiovascular disease.

4. Infection — it’s been discovered that vitamin D deficiency is related to inflammation, a negative reaction of the immune system. Vitamin D deficiency has been associated with numerous inflammatory diseases, such as rheumatoid arthritis, lupus, inflammatory bowel disease (IBD) and types 1 diabetes.

5. Cholesterol — vitamin D regulates cholesterol amounts in the bloodstream: it’s been demonstrated that without adequate sunlight exposure, vitamin D precursors turn to cholesterol rather than vitamin D.

6. Allergies — Studies demonstrate that kids who had reduced levels of vitamin D are more likely to have several food allergies.

7. Flu — Some research demonstrated a connection between insufficient vitamin D and frequent respiratory ailments, and suggest that individuals who have the lowest vitamin D levels report with considerably more cases of influenza and cold than people with greater degrees.

8. Anxiety — Vitamin D deficiency is connected to melancholy: receptors for vitamin D are found on several regions of the brain and are involved in several brain procedures, which makes it possible that this vitamin may be related to depression which vitamin D supplements may play an essential part in treating depression.

9. Type-2 Diabetes — Studies have shown correlations between low vitamin D levels and the progression of type two diabetes. Various studies offer evidence that vitamin D can promote glucose tolerance through its effects on insulin secretion and insulin sensitivity.

10. Cosmetic health — Several recent reports reveal a substantial association between periodontal health and also the consumption of vitamin D. Also older patients with low vitamin D levels have a greater rate of tooth loss than people with higher vitamin D levels.

11. Rheumatoid arthritis — Low vitamin D can play a part in developing rheumatoid arthritis. Studies have found that girls who get more vitamin D appear less inclined to become rheumatoid arthritis. Also among individuals who have rheumatoid arthritis, people who have low vitamin D levels have a tendency to have more lively symptoms.

12. Cancer — vitamin D deficiency can be associated with cancer: a specific study demonstrated that more than 75 percent of people who have an assortment of cancers have elevated levels of vitamin D, along with the lowest levels are correlated with more advanced cancers. Yet further research must ascertain whether greater vitamin D levels have been associated with reduced cancer incidence or death prices.

13. Dementia — Dementia is a chronic and progressive syndrome. It is an umbrella term, under which many diseases and ailments are categorized. The most common kind of dementia is Alzheimer’s disease.

Other common forms include cardiovascular disease, dementia with Lewy Bodies and frontotemporal dementia. You will find over 35.6 million individuals living with dementia globally, and a brand new instance emerges every 7 minutes.


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Currently, scientists connected vitamin D deficiency using a considerably higher risk of dementia and Alzheimer’s disease in elderly individuals. The study findings are extremely beneficial and open up new possibilities in this field of healthcare and prevention.

The dementia study printed in Neurology was conducted by a global group of investigators. 1,658 adults aged 65 and above were included in the analysis and followed over a period of six decades.

The participants needed to have the ability to walk unaided and so were free of dementia, cardiovascular disease and stroke at the onset of the analysis. It had been found that adults who had been deficient in vitamin D (their vitamin D levels were between 25 and 50 nanomoles per liter) had a 53% increased risk of developing dementia of any sort.

The danger increased to 125 percent in those who were seriously deficient (their vitamin D levels were under 25). For Alzheimer’s disease, the threat was 69 percent higher for those who had been moderately paralyzed, and 122 percent greater for the badly deficient group.

Past studies have shown that there’s a link between low vitamin D levels and growth of cognitive issues, but that is the earliest and most powerful study that demonstrated the substantial risk of dementia and Alzheimer’s disease in people with vitamin D deficiency.

Among those researchers, Dr. David Llewellyn in the University of Exeter Medical School points out that additional clinical studies are required to ascertain whether eating vitamin D rich foods or taking supplements may delay or even prevent the onset of Alzheimer’s disease and dementia.

Things to do if you’ve got a vitamin D deficiency?

Speak with your doctor if you are worried about the degree of vitamin D you receive from sunlight and your daily diet. A simple blood test may determine whether you have vitamin D deficiency. Your health care provider can advise if you have to have a vitamin D supplement. There’s not any consensus on why vitamin D levels necessary for optimum wellness, and it differs based on age and health conditions.

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